MULTIPLE SCLEROSIS AND RELATED DISORDERS

Agnese Peruzzi, Andrea Cereatti, Ugo Della Croce, Anat Mirelman

Overview

Multiple sclerosis (MS) causes gait and cognitive problems, which are exacerbated by dual-task walking. TM training has previously been used to preserve locomotor activity in MS. VR engages the user in both cognitive and motor activities at the same time. 

Objectives: 

This study aims at investigating the feasibility of a VR-based TM training program on gait of subjects with MS.

Method: 

A six-week VR-based TM training program was conducted with eight patients with relapsing-remitting MS. The gait analysis was conducted both for single and dual tasks. Walking endurance and obstacle negotiation were assessed using clinical tests. Evaluations were conducted before, immediately after, and one month after the training.

Findings:

In dual task following the intervention, stride length and gait speed improved. The ability to negotiate obstacles also improved. A VR-based TM training program is feasible and safe for MS patients with moderate disabilities, and may have a positive effect on gait in conditions such as dual tasking and obstacle navigating.

The V-TIME academic research project that has led to many of these papers is implemented commercially by GaitBetter.